
一、基本信息
李玉保,博士,教授,药学与食品工程学院(哈瓦那学院)党委副书记、执行院长
二、个人简介
李玉保,博士,教授,现任药学与食品工程学院(哈瓦那学院)党委副书记、执行院长,聊城大学硕士生导师,山东农业大学博士生导师,中国病理生理学会常务理事,中国病理生理学会动物病理生理学专业委员会主任委员,中国畜牧兽医学会动物福利与健康养殖分会 副理事长。主要从事动物细菌病防控及噬菌体研发,先后主持国家自然科学基金、科技部常规性科技援助项目等省级以上科研项目9项,主持横向课题20余项,主持农业部新农科研究与改革实践项目等省级以上教学研究项目3项。近年来,在专业学术刊物上共发表论文150余篇,其中SCI收录论文45篇,出版著作3部,获山东省教学成果奖一等奖1项、二等奖1项,山东省科技兴农奖优秀项目一等奖1项。
三、研究方向
动物致病菌及噬菌体研究。
四、主讲课程
《动物病理解剖》等。
五、科研项目
1. 国家自然科学基金,禽大肠杆菌T5样噬菌体宿主范围决定区关键氨基酸泛化及生物学特性研究(32372957),50万,2024.1-2027.12,主持;
2. 科技部常规性科技援助项目,南太平洋岛国种养技术研究与示范(KY202204002),200万,2022.11-2025.10,主持;
3. 山东省自然科学基金项目,mtHSP60/naïve HSP60 对MSB1 细胞凋亡调节作用及分子机制(ZR2020MC175),10万,2021.01-2023.12,主持;
4. 山东省农业科技园区产业提升工程项目,甲鱼高效养殖及功能性饮料技术研发与示范(2019YQ036),100万,2019.8-2022.8,主持;
5. 山东省重点研发计划,禽致病性大肠杆菌噬菌体分离鉴定、组合及临床应用研究(2019QYTPY011),20万,2019.1-2021.12,主持;
六、代表成果
1. Shengliang Cao, Wenwen Yang, Xihui Zhu, Cheng Liu, Jianbiao Lu, Zhenshu Si, Lanying Pei, Leilei Zhang, Wensi Hu, Yanlan Li, Zhiwei Wang, Zheyu Pang, Xijuan Xue, Yubao Li*. Isolation and identification of the broad‑spectrum high‑efficiency phage vB_SalP_LDW16 and its therapeutic application in chickens. BMC Veterinary Research, 2022, 18:386.
2. Duanduan Chen*, Zhiwei Wang, Shengliang Cao, Jianbiao Lu, Cheng Liu, Lingling Yang, Xusheng Du, Hui Wang, Yubao Li*. Molecular characterization and functional analysis of interferon regulatory factor-4 in the Red Claw Crayfish (Cherax quadricarinatus). Aquaculture Reports, 2022, https://doi.org/10.1016/j.aqrep.2022.101456.
3. Xihui Zhu, Yanlan Li, Zhiwei Wang, Zheyu Pang, Zhenshu Si, Cheng Liu, Jianbiao Lu, Shengliang Cao, Lanying Pei, Yubao Li*. Antibiotic resistance of Riemerella anatipestifer and comparative analysis of antibiotic-resistance gene detection methods. Poultry science, 2022, 102(3): 102405. Doi:10.1016/j.psj.2022.102405
4. Zhiwei Wang, Hui Wang b, Duanduan Chen*, Yubao Li*. Genomic Characterization and Comparative Genomic Analysis of Pathogenic Vibrio Isolated from Aquaculture-grown White-leg shrimp (Penaeus vannamei) in Guangdong and Jiangsu, China. Aquaculture, 2024, 580: 740302.
5. Zhu Xihui, Tang Luqi, Wang Zhiwei, Xie Feng, Zhang Wei*, Li Yubao*. A comparative analysis of phage classification methods in light of the recent ICTV taxonomic revisions. Virology, 2024, 594: 110016
6. Xiaoting Li, Tao Chen*,Qinghai Ren, Jianbiao Lu, Shengliang Cao, Cheng Liu, Yubao Li*. Phages in sludge from the A/O wastewater treatment process play an important role in the transmission of ARGs. Sci Total Environ, 2024, 926: 172111
7. Yanlan Li, Shengliang Cao, Yubao Li*. Mechanistic study of heat shock protein 60-mediated apoptosis in DF-1 cells. Poultry Science , 2024, 103:103619.
8. Yucui Huang, Zheyu Pang, Xinyang Zhu, Jiaxin Wang, Xiaojie Gao, Duanduan Chen, Cheng Liu, Jianbiao Lu, Zhenshu Si, Lanying Pei, Minge Wang, Shengliang Cao*, Yubao Li*. Characterization and genomic analysis of a broad-spectrum lytic phage vB_EcoM_SD350 and its application on raw chicken and beef meats against Avian pathogenic Escherichia coli. Food science and technology, 2025, 222: 117618.
9. Xinyang Zhu, Yucui Huang, Yuxia Shi, Xiaojie Gao, Duanduan Chen, Cheng Liu, Shengliang Cao, Xijuan Xue, Yubao Li*. Comparative genomic analysis of food-animal-derived and human-derived Clostridium perfringens isolates from markets in Shandong, China. Front. Microbiol, 2025, 16:1543511.
10. Yanlan Li, Zetong Huang, Xihui Zhu , Cheng Liu, Shengliang Cao, Yubao Li *. Serotyping, molecular typing, and vaccine protein screening for Riemerella anatipestifer: Overcoming challenges in prevention and treatment, Veterinary Microbiology, 2025, 309: 110663. 202508.
七、奖励荣誉
1. 构建“农业标准+技能实训+能力提升”职业教育模式,助推脱贫攻坚,山东省省级教学成果奖一等奖(2022)
2. 政产学研用深度融合,赋能生物医药类研究生创新能力提升的探索与实践,山东省第十届高等教育省级教学成果奖(研究生)二等奖(2025)
